Facebook (FB) is about to take its most intrusive advertising to a new medium – video – and it could be the most annoying yet.

On tap: short video ads placed smack in the middle of users’ main news feeds.

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Un-skippable Facebook video ads might seem like the greatest innovation in decades for major marketers, who have been coping with diminishing and fragmented television audiences for decades. Facebook says 88 million to 100 million people are on the service during primetime TV hours, almost as many people who watched this year’s Super Bowl.

But users might revolt; it’s happened before, many times before.

After all, people are flocking to social networks to see cute pictures and silly posts from friends and family, not to sit through ads for pickup trucks, allergy pills and fast food.

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Angry users could revive the “Quit Facebook Day” protest from 2011, when a change in privacy settings sparked criticism. But the organizers’ website ended up with only 40,620 “committed Facebook quitters,” a drop in the bucket for the huge social network.

And there are some reasons to believe that Facebook will succeed.

Last week, additional details about the video advertising leaked out. Ads will run only 15 seconds and users won’t see more than three per day, Bloomberg reported. And advertisers will be charged up to $2.5 million per day – more expensive per second than a TV ad on this year’s Super Bowl broadcast, which went for $4 million per 30 seconds.

Facebook declined to comment.

Currently, the site allows advertisers to embed video ads in posts, which users only see if they subscribe to the advertisers' feed, limiting the audience to a fraction of Facebook’s users base.

But Facebook has already set a precedent for putting unavoidable ads in the main news feed. Starting last year, advertisers could buy spots to run text and picture ads in the feed. The innovation brought few complaints and much new ad revenue and helped the company report a 53% jump in second quarter sales from last year.

Facebook CEO Mark Zuckerberg said last month that the company found no “meaningful drop” in customer satisfaction when it polled people who saw the static ads in their feeds versus those whose feeds were ad free. Facebook isn't planning to start putting ads yet on Instagram, the photo posting network it bought last year for $1 billion, Zuckerberg added.

Google’s YouTube site has slowly but surely been increasing its video advertising without drawing significant criticism. Still, only about 14% of YouTube videos played have ads, according to analyst Rory Maher.