Got $1,000? 2 Magnificent Growth Stocks to Buy and Hold Forever

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Many growth stocks have experienced pressure over the last few years as investor sentiment has shifted amid the changing macroeconomic backdrop. While no one can predict what the market will do next, if you're investing for five, 10, or 15 years in quality businesses, near-term market movements shouldn't deter you from putting cash to work.

If you're looking for top growth stocks to add to your portfolio right now, here are two names to consider for your buy list.

1. Vertex Pharmaceuticals

Vertex Pharmaceuticals (NASDAQ: VRTX) has grown into a veritable giant over the last decade with its leadership in the cystic fibrosis therapeutics market. The company bears the distinction of being the only name in the industry with drugs approved that treat the root genetic cause of this disease. In fact, one of the linchpins in Vertex's business strategy is focusing on rare diseases or underserved disease areas for which there are minimal to no viable treatment options and developing treatments that target the root cause of these conditions.

The most recent approval for Vertex was Casgevy, the product of a long-standing partnership with CRISPR Therapeutics. Not only is Casgevy designed to be a one-time functional cure for both sickle cell disease (SCD) and transfusion-dependent beta thalassemia (TDT), but it was also the first CRISPR therapy approved in history.

Because Casgevy is a gene-editing therapy, administration is a lengthy and highly involved process. Patients must prep to have their blood stem cells collected for around two months, and once they are collected, editing the cells for reinfusion takes anywhere from five to six months. Then, the patient must undergo chemotherapy before they can receive Casgevy, after which there is a recovery period.

Beyond the timeline to administer Casgvey, the therapy's $2.2 million price tag brings unique considerations for payers, so Vertex's ability to execute solid reimbursement agreements with public and private payers will be key. Vertex has actively been working alongside payers to achieve this goal. For example, in August, the company announced that it had reached a reimbursement agreement with England's National Health Service for eligible TDT patients to receive Casgevy.

While momentum from the gene-editing therapy will take time to manifest on the top and bottom lines, analysts think that Casgevy will bring in an additional $3 billion or more annually for Vertex in the future.

Beyond recent developments with Casgevy, Vertex has been going from strength to strength in other areas. It's awaiting approval for a new triple-combination cystic fibrosis therapy that could be even more effective than its existing flagship therapy, Trikafta. The company is also working on securing the regulatory green light for suzetrigine, its non-opioid drug for moderate to severe acute pain. Suzetrigine is also being studied as a treatment for diabetic peripheral neuropathy.