Krystal Biotech, Inc. (KRYS): Promising Pipeline or Risky Gamble?

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We recently published a list of 10 Worst Booming Stocks to Buy According to Short Sellers. In this article, we are going to take a look at where Krystal Biotech, Inc. (NASDAQ:KRYS) stands against other worst booming stocks to buy according to short sellers.

Are We Really In September?

September has historically been one of the worst months for US stocks. Considering this and the performance of big tech, particularly AI stocks, in the first week of the month, many investors have been shocked by the performance of the S&P 500 and the Nasdaq Composite Index in the second week of September. Both indices showcased their best performance this year during this week, and both were up for five days in a row. So, it’s not surprising that many investors are confused about what this means and how this even came about in the first place.

According to Tom Lee, Co-founder and Managing Partner at Fundstrat Global Advisors, this is the type of performance investors can expect to see over the next eight weeks up to Election Day – and perhaps even for a couple of weeks after that. With the much-awaited Fed meeting also coming up next week, Lee expects more support especially since we already have enough reason to believe that the Fed is going to make some cuts. According to Lee, with the inflation data coming in better than before and with the labor markets needing more support, the Fed’s actions will give the markets more confidence. This will translate into stocks trading well in the upcoming weeks.

Expected Future Trends

Lee noted that, at least for the next 12 months, investors should be more confident about the markets and their performance. The potential rate cut is not the only reason for this. Another positive factor is the upcoming election – according to Lee, historically, the markets have always performed well in the months coming after an election. This past trend is making the November-December period also look good for stocks in the US. Lee also commented that the policies of both Presidential candidates are good enough for the markets to do well in 2025 as well. So, even if investors see a little more turbulence, the long-term expectations for the market seem largely positive.

In terms of what stocks investors should be looking at in this new environment, Lee noted that the general rule for any investor should be to buy the best companies in any area first. These would be the companies that are able to beat any type of cycle and promise high returns to their shareholders, basically blue chip stocks. At the same time, Lee expects that when the Fed moves rates back toward neutral, cyclical and small-cap stocks will also benefit immensely from the tailwinds created by this move. Because of this, Lee expects small-caps to do really well in the next 12 months.

These insights have highlighted that the markets are now on an upward growth trajectory, and we’ve been seeing a lot of stocks generate immense returns because of this. However, many such booming stocks are being relentlessly shorted, which may brew confusion among investors about which companies to buy now. We’ve thus compiled a list of some booming stocks that short sellers consider to be the worst players in the market and explained whether you should consider buying them or not.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 275% since May 2014, beating its benchmark by 150 percentage points. (see more details here).

Krystal Biotech, Inc. (KRYS): Promising Pipeline or Risky Gamble?

A medical professional in a lab, analyzing gene therapy solutions toprevent rare diseases.

Krystal Biotech, Inc. (NASDAQ:KRYS)

Year-to-Date Performance as of September 14: 61.3%

Short % of Shares Outstanding as of September 14: 12.9%

Number of Hedge Fund Holders: 27

Krystal Biotech, Inc. (NASDAQ:KRYS) is a biotech company based in Pittsburgh, Pennsylvania. It develops genetic medicines for patients with rare diseases in the US.

The primary reason why investors are following Krystal Biotech, Inc. (NASDAQ:KRYS) is its pipeline. It currently has multiple early-stage clinical trials that are expected to make progress in the near future, including studies testing treatments for cystic fibrosis, solid tumors, and autosomal recessive congenital ichthyosis. However, many are skeptical about Krystal Biotech, Inc. (NASDAQ:KRYS) since these are only trial-stage treatments and thus do not offer solid reasons for why they should invest in the company.

Krystal Biotech, Inc. (NASDAQ:KRYS) has gotten FDA approval for one of its treatments, Vyjuvek, a gene therapy for dystrophic epidermolysis bullosa, which is a rare skin disease. However, this is only one approval, and that is for a small market in the US. Krystal Biotech, Inc. (NASDAQ:KRYS) estimates that only 9,000 people in the world suffer from this disease. Considering this, many short sellers consider this stock to be too risky.

Still, this level of risk is intrinsic for almost every biotech company out there. And Krystal Biotech, Inc. (NASDAQ:KRYS) does have encouraging share price growth to warrant a degree of positive investor attention.

At the end of the second quarter, 27 hedge funds were long Krystal Biotech, Inc. (NASDAQ:KRYS), with a total stake value of $877.2 million.

TimesSquare Capital Management mentioned Krystal Biotech, Inc. (NASDAQ:KRYS) in its first-quarter 2024 investor letter:

Our preferences among Health Care stocks are those companies providing novel therapies for unmet needs that deserve premium pricing, or specialized service providers. Krystal Biotech, Inc. (NASDAQ:KRYS), a gene therapy company, soared 42% and we trimmed the position. Their fourth quarter sales surpassed Street estimates by a wide margin. Of note, there is now a reduced time for getting approval for Vyjuvek to treat eye lesions in patients suffering from dystrophic epidermolysis bullosa (blistering of skin).

Overall, KRYS ranks 4th on our list of 10 worst booming stocks to buy according to short sellers. While we acknowledge the potential of KRYS as an investment, we believe that AI stocks hold promise for delivering high returns and doing so within a shorter timeframe. If you are looking for an AI stock that is more promising than KRYS but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.

 

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Disclosure: None. This article is originally published at Insider Monkey.