Planegg/Martinsried, September 16, 2024. Medigene AG (Medigene or the “Company”, FSE: MDG1, Prime Standard), an oncology platform company focused on the research and development of T cell receptor (TCR)-guided therapies for the treatment of cancer, will host an R&D Event on Medigene’s optimal 3S (specific, sensitive, and safe) TCRs for TCR-guided precision immunotherapies on Thursday, October 10, 2024, at 4.30 pm CET / 10:30 am ET. A live Q&A session will follow the formal presentations and discussions.

Management will discuss the advantages of the Company’s 3S TCRs across a wide range of modalities, including TCR-engineered T cell (TCR-T) therapies, TCR-guided T cell engager therapies (TCR-TCE), and TCR-natural killer cell therapies (TCR-NK).

Additionally, Principal Investigator of the EPITOME1015-I trial, Dr. David B. Zhen, MD, Associate Professor at both the Fred Hutchinson Cancer Center and the University of Washington School of Medicine, will provide a comprehensive overview of the Company’s lead program, MDG1015. His presentation will highlight the innovative approach taken with Medigene's lead third generation TCR-T therapy program, MDG1015, which targets the unmet needs that remain for treating solid tumors, despite recently approved first generation TCR-T therapies.

Finally, the presentation will cover Medigene’s proprietary End-to-End Platform, where multiple technologies can be deployed in a modular approach to generate multiple TCR-guided modalities, both cellular and antibody based, along with the latest advancements.

Attendees are invited to listen to the presentations and discussions as well as participate in the Q&A session.

Full details for the webcast and registration are as follows:

Following the call, an archived webcast will also be accessible on the Investors & Media section of the Medigene website https://www.medigene.com/investors-media/reports-presentations

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About Medigene AG

Medigene AG (FSE: MDG1) is an immuno-oncology platform company dedicated to developing T cell receptor (TCR)-guided therapies to effectively eliminate cancer. Its End-to-End Platform generates optimal 3S (sensitive, specific and safe) T cell receptors with unique and distinctive attributes that are utilized in multiple therapeutic modalities, such as T cell receptor engineered T cell (TCR-T) therapies, TCR-guided T cell engager therapies and TCR-natural killer cell therapies for both its in-house product pipeline and partnering.